Extreme Angiographic-Physiologic Mismatch With Elevated Left Ventricular End-Diastolic Pressure.

Translesional coronary pressure measures the hemodynamic significance of epicardial coronary artery disease. Angiographic-physiologic mismatching is attributed mainly to imaging limitations. We present a patient with extreme visual-physiologic functional mismatch and a markedly elevated left ventricular end diastolic pressure (LVEDP) as a potential contributory mechanism.